Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Starting Dose

BACKGROUND: Bodyweight-based dosing of tacrolimus (Tac) is considered standard care, even though the available evidence is thin. An increasing proportion of transplant recipients is overweight, prompting the question if the starting dose should always be based on bodyweight. METHODS: For this analys...

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發表在:Transplant Direct
Main Authors: Andrews, Louise M., de Winter, Brenda C.M., Tang, Jiang-Tao, Shuker, Nauras, Bouamar, Rachida, van Schaik, Ron H.N., Koch, Birgit C.P., van Gelder, Teun, Hesselink, Dennis A.
格式: Artigo
語言:Inglês
出版: Lippincott Williams & Wilkins 2017
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367746/
https://ncbi.nlm.nih.gov/pubmed/28361113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000644
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