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Histone deacetylase-high mobility group box-1 pathway targeted by hypaconitine suppresses the apoptosis of endothelial cells

Hypaconitine is an active component of Aconitum carmichaelii Debx, a Chinese medicinal herb for the treatment of cardiovascular diseases, but the mechanism underlying its effect remains elusive. In this study, we found that hypaconitine, rather than aconitum alkaloids in A. carmichaelii (e.g. aconit...

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Podrobná bibliografie
Vydáno v:Exp Biol Med (Maywood)
Hlavní autoři: Bai, Ye, Du, Shaohui, Li, Fei, Huang, Fengyuan, Deng, Rudong, Zhou, Jianhong, Chen, Dongfeng
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367659/
https://ncbi.nlm.nih.gov/pubmed/28056545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216685433
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