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Reactivation of p53 by MDM2 inhibitor MI-77301 for the treatment of endocrine-resistant breast cancer

Endocrine therapy has been highly effective for the treatment of estrogen-receptor positive breast cancer, but endocrine resistance develops in a significant proportion of patients. In an effort to develop novel therapeutic strategies for the treatment of endocrine resistant breast cancer, we have e...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Lu, Jianfeng, McEachern, Donna, Li, Shunqiang, Ellis, Matthew J., Wang, Shaomeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367629/
https://ncbi.nlm.nih.gov/pubmed/27765850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0028
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