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Immunostimulatory Effects of Melphalan and Usefulness in Adoptive Cell Therapy with Antitumor CD4+ T Cells

The alkylating agent melphalan is used in the treatment of hematological malignancies, especially multiple myeloma. In the past, the usefulness of melphalan has been solely attributed to its cytotoxicity on fast-growing cancerous cells. Although the immunomodulatory effects of melphalan were suggest...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Crit Rev Immunol
Prif Awduron: Kuczma, Michal, Ding, Zhi-Chun, Zhou, Gang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367467/
https://ncbi.nlm.nih.gov/pubmed/27910767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1615/CritRevImmunol.2016017507
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