(2S)-2-(3-(1-Carboxy-5-(4-(211)At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy

Alpha-particle emitters have a high linear energy transfer and short range, offering the potential for treating micrometastases while sparing normal tissues. We developed a urea-based, (211)At-labeled small molecule targeting prostate-specific membrane antigen (PSMA) for the treatment of micrometast...

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Detalles Bibliográficos
Publicado en:J Nucl Med
Autores principales: Kiess, Ana P., Minn, Il, Vaidyanathan, Ganesan, Hobbs, Robert F., Josefsson, Anders, Shen, Colette, Brummet, Mary, Chen, Ying, Choi, Jaeyeon, Koumarianou, Eftychia, Baidoo, Kwamena, Brechbiel, Martin W., Mease, Ronnie C., Sgouros, George, Zalutsky, Michael R., Pomper, Martin G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society of Nuclear Medicine 2016
Materias:
Basic Science Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367442/
https://ncbi.nlm.nih.gov/pubmed/27230930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.116.174300
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