(2S)-2-(3-(1-Carboxy-5-(4-(211)At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy

Alpha-particle emitters have a high linear energy transfer and short range, offering the potential for treating micrometastases while sparing normal tissues. We developed a urea-based, (211)At-labeled small molecule targeting prostate-specific membrane antigen (PSMA) for the treatment of micrometast...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Kiess, Ana P., Minn, Il, Vaidyanathan, Ganesan, Hobbs, Robert F., Josefsson, Anders, Shen, Colette, Brummet, Mary, Chen, Ying, Choi, Jaeyeon, Koumarianou, Eftychia, Baidoo, Kwamena, Brechbiel, Martin W., Mease, Ronnie C., Sgouros, George, Zalutsky, Michael R., Pomper, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2016
Assuntos:
Basic Science Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367442/
https://ncbi.nlm.nih.gov/pubmed/27230930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.116.174300
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