(2S)-2-(3-(1-Carboxy-5-(4-(211)At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy

Alpha-particle emitters have a high linear energy transfer and short range, offering the potential for treating micrometastases while sparing normal tissues. We developed a urea-based, (211)At-labeled small molecule targeting prostate-specific membrane antigen (PSMA) for the treatment of micrometast...

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Опубликовано в: :J Nucl Med
Главные авторы: Kiess, Ana P., Minn, Il, Vaidyanathan, Ganesan, Hobbs, Robert F., Josefsson, Anders, Shen, Colette, Brummet, Mary, Chen, Ying, Choi, Jaeyeon, Koumarianou, Eftychia, Baidoo, Kwamena, Brechbiel, Martin W., Mease, Ronnie C., Sgouros, George, Zalutsky, Michael R., Pomper, Martin G.
Формат: Artigo
Язык:Inglês
Опубликовано: Society of Nuclear Medicine 2016
Предметы:
Basic Science Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367442/
https://ncbi.nlm.nih.gov/pubmed/27230930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.116.174300
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