(2S)-2-(3-(1-Carboxy-5-(4-(211)At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy

Alpha-particle emitters have a high linear energy transfer and short range, offering the potential for treating micrometastases while sparing normal tissues. We developed a urea-based, (211)At-labeled small molecule targeting prostate-specific membrane antigen (PSMA) for the treatment of micrometast...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Nucl Med
Auteurs principaux: Kiess, Ana P., Minn, Il, Vaidyanathan, Ganesan, Hobbs, Robert F., Josefsson, Anders, Shen, Colette, Brummet, Mary, Chen, Ying, Choi, Jaeyeon, Koumarianou, Eftychia, Baidoo, Kwamena, Brechbiel, Martin W., Mease, Ronnie C., Sgouros, George, Zalutsky, Michael R., Pomper, Martin G.
Format: Artigo
Langue:Inglês
Publié: Society of Nuclear Medicine 2016
Sujets:
Basic Science Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367442/
https://ncbi.nlm.nih.gov/pubmed/27230930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.116.174300
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