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An indigenous posttranscriptional modification in the ribosomal peptidyl transferase center confers resistance to an array of protein synthesis inhibitors

A number of nucleotide residues in ribosomal RNA undergo specific posttranscriptional modification. The roles of most modifications are unclear, but their clustering in the functionally-important regions of rRNA suggest that they might either directly affect the activity or assembly of the ribosome...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Mol Biol
Main Authors: Toh, Seok-Ming, Mankin, Alexander S.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367387/
https://ncbi.nlm.nih.gov/pubmed/18554609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.027
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