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PR-Independent Neurosteroid Regulation of α2-GABA-A Receptors in the Hippocampus Subfields
Progesterone (P) binding to the intracellular progesterone receptors (PRs) plays a key role in epilepsy via modulation of GABA-A receptor plasticity in the brain. This is thought to occur via conversion of P to neurosteroids such as allopregnanolone, an allosteric modulator of GABA-A receptors. In t...
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| Publié dans: | Brain Res |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5367384/ https://ncbi.nlm.nih.gov/pubmed/28137424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2017.01.030 |
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