Silencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy

Overexpression of BMI1 in human cancer cells, a member of the polycomb group of repressive complexes, correlates with advanced stage of disease, aggressive clinico-pathological behavior, poor prognosis, and resistance to radiation and chemotherapy. Studies have shown that experimental reduction of B...

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Vydáno v:Oncol Rep
Hlavní autoři: Griffith, James, Andrade, Daniel, Mehta, Meghna, Berry, William, Benbrook, Doris M., Aravindan, Natarajan, Herman, Terence S., Ramesh, Rajagopal, Munshi, Anupama
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367353/
https://ncbi.nlm.nih.gov/pubmed/28260023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5478
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