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YAP1 inhibition radiosensitizes triple negative breast cancer cells by targeting the DNA damage response and cell survival pathways

The Hippo pathway is an evolutionarily conserved signaling pathway that regulates proliferation and apoptosis to control organ size during developmental growth. Yes-associated protein 1 (YAP1), the terminal effector of the Hippo pathway, is a transcriptional co-activator and a potent growth promoter...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Andrade, Daniel, Mehta, Meghna, Griffith, James, Panneerselvam, Janani, Srivastava, Akhil, Kim, Tae-Dong, Janknecht, Ralf, Herman, Terence, Ramesh, Rajagopal, Munshi, Anupama
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716745/
https://ncbi.nlm.nih.gov/pubmed/29228705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21913
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