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PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription
Transcription complexes that assemble at the HIV-1 promoter efficiently initiate transcription but generate paused RNA polymerase II downstream from the start site. The virally encoded Tat protein hijacks positive transcription elongation factor b (P-TEFb) to phosphorylate and activate this paused p...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5366948/ https://ncbi.nlm.nih.gov/pubmed/28345603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45394 |
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