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Transition Step during Assembly of HIV Tat:P-TEFb Transcription Complexes and Transfer to TAR RNA

Transcription factors regulate eukaryotic RNA polymerase II (Pol II) activity by assembling and remodeling complexes at multiple steps in the transcription cycle. In HIV, we previously proposed a two-step model where the viral Tat protein first preassembles at the promoter with an inactive P-TEFb:7S...

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Detalhes bibliográficos
Main Authors: D'Orso, Iván, Jang, Gwendolyn M., Pastuszak, Alexander W., Faust, Tyler B., Quezada, Elizabeth, Booth, David S., Frankel, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497596/
https://ncbi.nlm.nih.gov/pubmed/23007159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00206-12
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