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Transition Step during Assembly of HIV Tat:P-TEFb Transcription Complexes and Transfer to TAR RNA

Transcription factors regulate eukaryotic RNA polymerase II (Pol II) activity by assembling and remodeling complexes at multiple steps in the transcription cycle. In HIV, we previously proposed a two-step model where the viral Tat protein first preassembles at the promoter with an inactive P-TEFb:7S...

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Bibliographische Detailangaben
Hauptverfasser: D'Orso, Iván, Jang, Gwendolyn M., Pastuszak, Alexander W., Faust, Tyler B., Quezada, Elizabeth, Booth, David S., Frankel, Alan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497596/
https://ncbi.nlm.nih.gov/pubmed/23007159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00206-12
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