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Mixed-linkage ubiquitin chains send mixed messages

Research on ubiquitin (Ub) signaling has focused primarily on homogeneously-linked polyUb. Although polyUb containing different linkages within the same chain exist, their structures and signaling properties are unknown. These mixed-linkage chains could be unbranched (i.e., no more than one lysine-...

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Detalhes bibliográficos
Main Authors: Nakasone, Mark A., Livnat-Levanon, Nurit, Glickman, Michael H., Cohen, Robert E., Fushman, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654000/
https://ncbi.nlm.nih.gov/pubmed/23562397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.02.019
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