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Copy number variation profile in the placental and parental genomes of recurrent pregnancy loss families

We have previously shown an extensive load of somatic copy number variations (CNVs) in the human placental genome with the highest fraction detected in normal term pregnancies. Hereby, we hypothesized that insufficient promotion of CNVs may impair placental development and lead to recurrent pregnanc...

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Publicat a:Sci Rep
Autors principals: Kasak, Laura, Rull, Kristiina, Sõber, Siim, Laan, Maris
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366903/
https://ncbi.nlm.nih.gov/pubmed/28345611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45327
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