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Copy number variation profile in the placental and parental genomes of recurrent pregnancy loss families

We have previously shown an extensive load of somatic copy number variations (CNVs) in the human placental genome with the highest fraction detected in normal term pregnancies. Hereby, we hypothesized that insufficient promotion of CNVs may impair placental development and lead to recurrent pregnanc...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kasak, Laura, Rull, Kristiina, Sõber, Siim, Laan, Maris
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366903/
https://ncbi.nlm.nih.gov/pubmed/28345611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45327
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