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RNA sequencing of chorionic villi from recurrent pregnancy loss patients reveals impaired function of basic nuclear and cellular machinery

Recurrent pregnancy loss (RPL) concerns ~3% of couples aiming at childbirth. In the current study, transcriptomes and miRNomes of 1(st) trimester placental chorionic villi were analysed for 2 RPL cases (≥6 miscarriages) and normal, but electively terminated pregnancies (ETP; n = 8). Sequencing was p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sõber, Siim, Rull, Kristiina, Reiman, Mario, Ilisson, Piret, Mattila, Pirkko, Laan, Maris
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143936/
https://ncbi.nlm.nih.gov/pubmed/27929073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38439
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