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Penetration of Ciprofloxacin and Amikacin into the Alveolar Epithelial Lining Fluid of Rats with Pulmonary Fibrosis

We determined the concentration-time profiles of ciprofloxacin and amikacin in serum and alveolar epithelial lining fluid (ELF) of rats with or without pulmonary fibrosis and investigated the effect of pulmonary fibrosis on the capacity for penetration of antimicrobials into the ELF of rats. Pulmona...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Ni, Wentao, Yang, Deqing, Mei, Hekun, Zhao, Jin, Liang, Beibei, Bai, Nan, Chai, Dong, Cui, Junchang, Wang, Rui, Liu, Youning
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365682/
https://ncbi.nlm.nih.gov/pubmed/28115351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01936-16
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