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Penetration of Ciprofloxacin and Amikacin into the Alveolar Epithelial Lining Fluid of Rats with Pulmonary Fibrosis

We determined the concentration-time profiles of ciprofloxacin and amikacin in serum and alveolar epithelial lining fluid (ELF) of rats with or without pulmonary fibrosis and investigated the effect of pulmonary fibrosis on the capacity for penetration of antimicrobials into the ELF of rats. Pulmona...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ni, Wentao, Yang, Deqing, Mei, Hekun, Zhao, Jin, Liang, Beibei, Bai, Nan, Chai, Dong, Cui, Junchang, Wang, Rui, Liu, Youning
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365682/
https://ncbi.nlm.nih.gov/pubmed/28115351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01936-16
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