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Penetration of Ciprofloxacin and Amikacin into the Alveolar Epithelial Lining Fluid of Rats with Pulmonary Fibrosis

We determined the concentration-time profiles of ciprofloxacin and amikacin in serum and alveolar epithelial lining fluid (ELF) of rats with or without pulmonary fibrosis and investigated the effect of pulmonary fibrosis on the capacity for penetration of antimicrobials into the ELF of rats. Pulmona...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Ni, Wentao, Yang, Deqing, Mei, Hekun, Zhao, Jin, Liang, Beibei, Bai, Nan, Chai, Dong, Cui, Junchang, Wang, Rui, Liu, Youning
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365682/
https://ncbi.nlm.nih.gov/pubmed/28115351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01936-16
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