The Mechanism of Killing by the Proline-Rich Peptide Bac7(1–35) against Clinical Strains of Pseudomonas aeruginosa Differs from That against Other Gram-Negative Bacteria

Pseudomonas aeruginosa infections represent a serious threat to worldwide health. Proline-rich antimicrobial peptides (PR-AMPs), a particular group of peptide antibiotics, have demonstrated in vitro activity against P. aeruginosa strains. Here we show that the mammalian PR-AMP Bac7(1–35) is active a...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Runti, Giulia, Benincasa, Monica, Giuffrida, Grazia, Devescovi, Giulia, Venturi, Vittorio, Gennaro, Renato, Scocchi, Marco
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Mechanisms of Action: Physiological Effects
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365664/
https://ncbi.nlm.nih.gov/pubmed/28137800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01660-16
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