Fragments of the Nonlytic Proline-Rich Antimicrobial Peptide Bac5 Kill Escherichia coli Cells by Inhibiting Protein Synthesis

Unlike most antimicrobial peptides (AMPs), the main mode of action of the subclass of proline-rich antimicrobial peptides (PrAMPs) is not based on disruption of the bacterial membrane. Instead, PrAMPs exploit the inner membrane transporters SbmA and YjiL/MdtM to pass through the bacterial membrane a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Mardirossian, Mario, Barrière, Quentin, Timchenko, Tatiana, Müller, Claudia, Pacor, Sabrina, Mergaert, Peter, Scocchi, Marco, Wilson, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105812/
https://ncbi.nlm.nih.gov/pubmed/29844040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00534-18
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