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Memantine Induces NMDAR1-Mediated Autophagic Cell Death in Malignant Glioma Cells

OBJECTIVE: Autophagy is one of the key responses of cells to programmed cell death. Memantine, an approved anti-dementia drug, has an antiproliferative effect on cancer cells but the mechanism is poorly understood. The aim of the present study was to test the possibility of induction of autophagic c...

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Vydáno v:J Korean Neurosurg Soc
Hlavní autoři: Yoon, Wan-Soo, Yeom, Mi-Young, Kang, Eun-Sun, Chung, Yong-An, Chung, Dong-Sup, Jeun, Sin-Soo
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Neurosurgical Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365296/
https://ncbi.nlm.nih.gov/pubmed/28264232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3340/jkns.2016.0101.006
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