BH3 Mimetics Reactivate Autophagic Cell Death in Anoxia-Resistant Malignant Glioma Cells

Here, we investigated the specific roles of Bcl-2 family members in anoxia tolerance of malignant glioma. Flow cytometry analysis of cell death in 17 glioma cell lines revealed drastic differences in their sensitivity to oxygen withdrawal (<0.1% O(2)). Cell death correlated with mitochondrial dep...

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Detalhes bibliográficos
Main Authors: Hetschko, Holger, Voss, Valerie, Senft, Christian, Seifert, Volker, Prehn, Jochen HM, Kögel, Donat
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481574/
https://ncbi.nlm.nih.gov/pubmed/18670645
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