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Memantine Induces NMDAR1-Mediated Autophagic Cell Death in Malignant Glioma Cells

OBJECTIVE: Autophagy is one of the key responses of cells to programmed cell death. Memantine, an approved anti-dementia drug, has an antiproliferative effect on cancer cells but the mechanism is poorly understood. The aim of the present study was to test the possibility of induction of autophagic c...

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Detalhes bibliográficos
Publicado no:J Korean Neurosurg Soc
Main Authors: Yoon, Wan-Soo, Yeom, Mi-Young, Kang, Eun-Sun, Chung, Yong-An, Chung, Dong-Sup, Jeun, Sin-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Neurosurgical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365296/
https://ncbi.nlm.nih.gov/pubmed/28264232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3340/jkns.2016.0101.006
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