Copper-catalyzed click reaction on/in live cells

We demonstrated that the copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction could be performed inside live mammalian cells without using a chelating azide. Under optimized conditions, the reaction was performed in human ovary cancer cell line OVCAR5 in which newly synthesized proteins were...

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Dettagli Bibliografici
Pubblicato in:Chem Sci
Autori principali: Li, Siheng, Wang, Lin, Yu, Fei, Zhu, Zhiling, Shobaki, Dema, Chen, Haoqing, Wang, Mu, Wang, Jun, Qin, Guoting, Erasquin, Uriel J., Ren, Li, Wang, Yingjun, Cai, Chengzhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2017
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365239/
https://ncbi.nlm.nih.gov/pubmed/28348729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02297a
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