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Anaerobic conditions to reduce oxidation of proteins and to accelerate the copper-catalyzed “Click” reaction with a water-soluble bis(triazole) ligand
Oxidation of protein (bovine albumin serum) by air still occurred under the copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction conditions even in the presence of a Cu(I)-stabilizing tris(triazole) ligand. Anaerobic conditions not only avoided the oxidation of the protein, but also greatly...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230266/ https://ncbi.nlm.nih.gov/pubmed/21283838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc05376g |
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