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Anaerobic conditions to reduce oxidation of proteins and to accelerate the copper-catalyzed “Click” reaction with a water-soluble bis(triazole) ligand

Oxidation of protein (bovine albumin serum) by air still occurred under the copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction conditions even in the presence of a Cu(I)-stabilizing tris(triazole) ligand. Anaerobic conditions not only avoided the oxidation of the protein, but also greatly...

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Detalhes bibliográficos
Main Authors: Kumar, Amit, Li, King, Cai, Chengzhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230266/
https://ncbi.nlm.nih.gov/pubmed/21283838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc05376g
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