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Superposition-free comparison and clustering of antibody binding sites: implications for the prediction of the nature of their antigen

We describe here a superposition free method for comparing the surfaces of antibody binding sites based on the Zernike moments and show that they can be used to quickly compare and cluster sets of antibodies. The clusters provide information about the nature of the bound antigen that, when combined...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Di Rienzo, Lorenzo, Milanetti, Edoardo, Lepore, Rosalba, Olimpieri, Pier Paolo, Tramontano, Anna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364466/
https://ncbi.nlm.nih.gov/pubmed/28338016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45053
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