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Superposition-free comparison and clustering of antibody binding sites: implications for the prediction of the nature of their antigen

We describe here a superposition free method for comparing the surfaces of antibody binding sites based on the Zernike moments and show that they can be used to quickly compare and cluster sets of antibodies. The clusters provide information about the nature of the bound antigen that, when combined...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Di Rienzo, Lorenzo, Milanetti, Edoardo, Lepore, Rosalba, Olimpieri, Pier Paolo, Tramontano, Anna
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364466/
https://ncbi.nlm.nih.gov/pubmed/28338016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45053
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