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Superposition-free comparison and clustering of antibody binding sites: implications for the prediction of the nature of their antigen

We describe here a superposition free method for comparing the surfaces of antibody binding sites based on the Zernike moments and show that they can be used to quickly compare and cluster sets of antibodies. The clusters provide information about the nature of the bound antigen that, when combined...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Di Rienzo, Lorenzo, Milanetti, Edoardo, Lepore, Rosalba, Olimpieri, Pier Paolo, Tramontano, Anna
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364466/
https://ncbi.nlm.nih.gov/pubmed/28338016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45053
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