Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20

Hepatic de novo lipogenesis (DNL) converts carbohydrates into triglycerides and is known to influence systemic lipid homoeostasis. Here, we demonstrate that the zinc finger protein Zbtb20 is required for DNL. Mice lacking Zbtb20 in the liver exhibit hypolipidemia and reduced levels of liver triglyce...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Liu, Gan, Zhou, Luting, Zhang, Hai, Chen, Rong, Zhang, Ye, Li, Ling, Lu, Jun-Yu, Jiang, Hui, Liu, Dong, Qi, Shasha, Jiang, Ying-Ming, Yin, Kai, Xie, Zhifang, Shi, Yuguang, Liu, Yong, Cao, Xuetao, Chen, Yu-Xia, Zou, Dajin, Zhang, Weiping J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364431/
https://ncbi.nlm.nih.gov/pubmed/28327662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14824
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