Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver

The alpha-fetoprotein (AFP) gene is highly activated in fetal liver but is dramatically repressed shortly after birth. The mechanisms that underlie AFP transcriptional repression in postpartum liver are not well understood. AFP enhancer, repressor region, and promoter are implicated to be involved i...

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Detalhes bibliográficos
Main Authors: Xie, Zhifang, Zhang, Hai, Tsai, Wenwei, Zhang, Ye, Du, Yu, Zhong, Jigen, Szpirer, Claude, Zhu, Minghua, Cao, Xuetao, Barton, Michelle Craig, Grusby, Michael J., Zhang, Weiping J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504784/
https://ncbi.nlm.nih.gov/pubmed/18669658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800647105
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