Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver

The alpha-fetoprotein (AFP) gene is highly activated in fetal liver but is dramatically repressed shortly after birth. The mechanisms that underlie AFP transcriptional repression in postpartum liver are not well understood. AFP enhancer, repressor region, and promoter are implicated to be involved i...

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Hlavní autoři: Xie, Zhifang, Zhang, Hai, Tsai, Wenwei, Zhang, Ye, Du, Yu, Zhong, Jigen, Szpirer, Claude, Zhu, Minghua, Cao, Xuetao, Barton, Michelle Craig, Grusby, Michael J., Zhang, Weiping J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504784/
https://ncbi.nlm.nih.gov/pubmed/18669658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800647105
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