Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20

Hepatic de novo lipogenesis (DNL) converts carbohydrates into triglycerides and is known to influence systemic lipid homoeostasis. Here, we demonstrate that the zinc finger protein Zbtb20 is required for DNL. Mice lacking Zbtb20 in the liver exhibit hypolipidemia and reduced levels of liver triglyce...

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Опубликовано в: :Nat Commun
Главные авторы: Liu, Gan, Zhou, Luting, Zhang, Hai, Chen, Rong, Zhang, Ye, Li, Ling, Lu, Jun-Yu, Jiang, Hui, Liu, Dong, Qi, Shasha, Jiang, Ying-Ming, Yin, Kai, Xie, Zhifang, Shi, Yuguang, Liu, Yong, Cao, Xuetao, Chen, Yu-Xia, Zou, Dajin, Zhang, Weiping J.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364431/
https://ncbi.nlm.nih.gov/pubmed/28327662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14824
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