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Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
Hepatic de novo lipogenesis (DNL) converts carbohydrates into triglycerides and is known to influence systemic lipid homoeostasis. Here, we demonstrate that the zinc finger protein Zbtb20 is required for DNL. Mice lacking Zbtb20 in the liver exhibit hypolipidemia and reduced levels of liver triglyce...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5364431/ https://ncbi.nlm.nih.gov/pubmed/28327662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14824 |
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