Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20

Hepatic de novo lipogenesis (DNL) converts carbohydrates into triglycerides and is known to influence systemic lipid homoeostasis. Here, we demonstrate that the zinc finger protein Zbtb20 is required for DNL. Mice lacking Zbtb20 in the liver exhibit hypolipidemia and reduced levels of liver triglyce...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Liu, Gan, Zhou, Luting, Zhang, Hai, Chen, Rong, Zhang, Ye, Li, Ling, Lu, Jun-Yu, Jiang, Hui, Liu, Dong, Qi, Shasha, Jiang, Ying-Ming, Yin, Kai, Xie, Zhifang, Shi, Yuguang, Liu, Yong, Cao, Xuetao, Chen, Yu-Xia, Zou, Dajin, Zhang, Weiping J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364431/
https://ncbi.nlm.nih.gov/pubmed/28327662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14824
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