Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20

Hepatic de novo lipogenesis (DNL) converts carbohydrates into triglycerides and is known to influence systemic lipid homoeostasis. Here, we demonstrate that the zinc finger protein Zbtb20 is required for DNL. Mice lacking Zbtb20 in the liver exhibit hypolipidemia and reduced levels of liver triglyce...

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Publicat a:Nat Commun
Autors principals: Liu, Gan, Zhou, Luting, Zhang, Hai, Chen, Rong, Zhang, Ye, Li, Ling, Lu, Jun-Yu, Jiang, Hui, Liu, Dong, Qi, Shasha, Jiang, Ying-Ming, Yin, Kai, Xie, Zhifang, Shi, Yuguang, Liu, Yong, Cao, Xuetao, Chen, Yu-Xia, Zou, Dajin, Zhang, Weiping J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364431/
https://ncbi.nlm.nih.gov/pubmed/28327662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14824
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