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Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme
Mutations in chromatin modifier genes are frequently associated with neurodevelopmental diseases. We herein demonstrate that the chromodomain helicase DNA-binding protein 7 (Chd7), frequently associated with CHARGE syndrome, is indispensable for normal cerebellar development. Genetic inactivation of...
Shranjeno v:
| izdano v: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5364396/ https://ncbi.nlm.nih.gov/pubmed/28317875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14758 |
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