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Biology and relevance of human acute myeloid leukemia stem cells

Evidence of human acute myeloid leukemia stem cells (AML LSCs) was first reported nearly 2 decades ago through the identification of rare subpopulations of engrafting cells in xenotransplantation assays. These AML LSCs were shown to reside at the apex of a cellular hierarchy that initiates and maint...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Thomas, Daniel, Majeti, Ravindra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364335/
https://ncbi.nlm.nih.gov/pubmed/28159741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-696054
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