The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1

By attaching infected erythrocytes to the vascular lining, Plasmodium falciparum parasites leave blood circulation and avoid splenic clearance. This sequestration is central to pathogenesis. Severe malaria is associated with parasites expressing an antigenically distinct P. falciparum erythrocyte me...

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Опубликовано в: :Infect Immun
Главные авторы: Mkumbaye, Sixbert I., Wang, Christian W., Lyimo, Eric, Jespersen, Jakob S., Manjurano, Alphaxard, Mosha, Jacklin, Kavishe, Reginald A., Mwakalinga, Steven B., Minja, Daniel T. R., Lusingu, John P., Theander, Thor G., Lavstsen, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364309/
https://ncbi.nlm.nih.gov/pubmed/28138022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00841-16
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