In Vivo Imaging of the Buccal Mucosa Shows Loss of the Endothelial Glycocalyx and Perivascular Hemorrhages in Pediatric Plasmodium falciparum Malaria

Severe malaria is mostly caused by Plasmodium falciparum, resulting in considerable, systemic inflammation and pronounced endothelial activation. The endothelium forms an interface between blood and tissue, and vasculopathy has previously been linked with malaria severity. We studied the extent to w...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Lyimo, Eric, Haslund, Lars Emil, Ramsing, Thomas, Wang, Christian William, Efunshile, Akinwale Michael, Manjurano, Alphaxard, Makene, Victor, Lusingu, John, Theander, Thor Grundtvig, Kurtzhals, Jørgen Anders Lindholm, Paulsen, Rasmus, Hempel, Casper
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035942/
https://ncbi.nlm.nih.gov/pubmed/31871101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00679-19
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