The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1

By attaching infected erythrocytes to the vascular lining, Plasmodium falciparum parasites leave blood circulation and avoid splenic clearance. This sequestration is central to pathogenesis. Severe malaria is associated with parasites expressing an antigenically distinct P. falciparum erythrocyte me...

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Bibliografiska uppgifter
I publikationen:Infect Immun
Huvudupphovsmän: Mkumbaye, Sixbert I., Wang, Christian W., Lyimo, Eric, Jespersen, Jakob S., Manjurano, Alphaxard, Mosha, Jacklin, Kavishe, Reginald A., Mwakalinga, Steven B., Minja, Daniel T. R., Lusingu, John P., Theander, Thor G., Lavstsen, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364309/
https://ncbi.nlm.nih.gov/pubmed/28138022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00841-16
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