Tamoxifen Directly Inhibits Platelet Angiogenic Potential and Platelet-Mediated Metastasis

OBJECTIVE: Platelets, which are mainly known for their role in hemostasis, are now known to play a crucial role in metastasis. Tamoxifen is a selective estrogen receptor modulator that is widely used for the treatment of breast cancer. Tamoxifen and its metabolites have been shown to directly impact...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Johnson, Kelly E., Forward, Jodi A., Tippy, Mason D., Ceglowski, Julia R., El-Husayni, Saleh, Kulenthirarajan, Rajesh, Machlus, Kellie R., Mayer, Erica L., Italiano, Joseph E., Battinelli, Elisabeth M.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364056/
https://ncbi.nlm.nih.gov/pubmed/28153880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308791
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