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Essential role of the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells

Innate-like B-1a cells provide a first line of defense against pathogens, yet little is known about their transcriptional control. Here we identified an essential role of the transcription factor Bhlhe41, with a lesser contribution of Bhlhe40, in controlling late stages of B-1a cell differentiation....

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Vydáno v:Nat Immunol
Hlavní autoři: Kreslavsky, Taras, Vilagos, Bojan, Tagoh, Hiromi, Kostanova Poliakova, Daniela, Schwickert, Tanja, Wöhner, Miriam, Jaritz, Markus, Weiss, Siegfried, Taneja, Reshma, Rossner, Moritz J., Busslinger, Meinrad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363839/
https://ncbi.nlm.nih.gov/pubmed/28250425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3694
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