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Mutation in TNXB gene causes moderate to severe Ehlers-Danlos syndrome

We report a 28-year-old female who presented with severe joint pain, chronic muscle weakness, Raynaud’s phenomenon, and hypermobility. She was found to have a 6074A > T nucleotide transition in the TNXB gene causing an amino acid protein change at Asp2025Val classified as likely pathogenic. We ad...

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Bibliografische gegevens
Gepubliceerd in:World J Med Genet
Hoofdauteurs: Kaufman, Carolyn S, Butler, Merlin G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363719/
https://ncbi.nlm.nih.gov/pubmed/28344932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5496/wjmg.v6.i2.17
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