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Epigenetic Activation of μ-Opioid Receptor Gene via Increased Expression and Function of Mitogen- and Stress-Activated Protein Kinase 1

Since the discovery of μ-opioid receptor (MOR) gene two decades ago, various regulatory factors have been shown to interact with the MOR promoter and modulate transcript levels. However, the majority of early transcriptional studies on MOR gene have not addressed how intracellular signaling pathways...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Pharmacol
Hauptverfasser: Wagley, Yadav, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363709/
https://ncbi.nlm.nih.gov/pubmed/28153853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.106567
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