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Epigenetic Activation of μ-Opioid Receptor Gene via Increased Expression and Function of Mitogen- and Stress-Activated Protein Kinase 1

Since the discovery of μ-opioid receptor (MOR) gene two decades ago, various regulatory factors have been shown to interact with the MOR promoter and modulate transcript levels. However, the majority of early transcriptional studies on MOR gene have not addressed how intracellular signaling pathways...

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Bibliografske podrobnosti
izdano v:Mol Pharmacol
Main Authors: Wagley, Yadav, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363709/
https://ncbi.nlm.nih.gov/pubmed/28153853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.106567
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