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Efficient generation of antigen-specific CTLs by the BAFF-activated human B Lymphocytes as APCs: a novel approach for immunotherapy

Efficient antigen presentation is indispensable for cytotoxic T lymphocyte (CTL)-mediated immunotherapy. B-lymphocytes propagated with CD40L have been developed as antigen-presenting cells (APCs), but this capacity needs further optimization. Here, we aimed to expand human B-lymphocytes on a large s...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Yiwen, Zhang, Shilin, Gao, Yingshi, Chen, Lishi, Su, Baohong, Luo, Chao, Liu, Linghua, Li, Ting, Pan, Hui, Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363617/
https://ncbi.nlm.nih.gov/pubmed/27780916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12792
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