PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection

Macrophage plasticity is critical for controlling inflammation including those produced by helminth infections, where alternatively activated macrophages (AAM) are accumulated in tissues. AAM expressing the co-inhibitory molecule programmed death ligand 2 (PD-L2), which is capable of binding program...

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Vydáno v:Oncotarget
Hlavní autoři: Stempin, Cinthia C., Motrán, Claudia C., Aoki, María P., Falcón, Cristian R., Cerbán, Fabio M., Cervi, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363616/
https://ncbi.nlm.nih.gov/pubmed/27783986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12790
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