PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection

Macrophage plasticity is critical for controlling inflammation including those produced by helminth infections, where alternatively activated macrophages (AAM) are accumulated in tissues. AAM expressing the co-inhibitory molecule programmed death ligand 2 (PD-L2), which is capable of binding program...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Stempin, Cinthia C., Motrán, Claudia C., Aoki, María P., Falcón, Cristian R., Cerbán, Fabio M., Cervi, Laura
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363616/
https://ncbi.nlm.nih.gov/pubmed/27783986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12790
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