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PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection

Macrophage plasticity is critical for controlling inflammation including those produced by helminth infections, where alternatively activated macrophages (AAM) are accumulated in tissues. AAM expressing the co-inhibitory molecule programmed death ligand 2 (PD-L2), which is capable of binding program...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Stempin, Cinthia C., Motrán, Claudia C., Aoki, María P., Falcón, Cristian R., Cerbán, Fabio M., Cervi, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363616/
https://ncbi.nlm.nih.gov/pubmed/27783986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12790
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