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Blocking hepatic metastases of colon cancer cells using an shRNA against Rac1 delivered by activatable cell-penetrating peptide

Hepatic metastasis is one of the critical progressions of colon cancer. Blocking this process is key to prolonging survival time in cancer patients. Studies on activatable cell-penetrating peptides (dtACPPs) have demonstrated their potential as gene carriers. It showed high tumor cell-targeting spec...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Bao, Ying, Guo, Huihui, Lu, Yongliang, Feng, Wenming, Sun, Xinrong, Tang, Chengwu, Wang, Xiang, Shen, Mo
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363579/
https://ncbi.nlm.nih.gov/pubmed/27791203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12854
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