טוען...
Type I Interferons Impede Short Hairpin RNA-Mediated RNAi via Inhibition of Dicer-Mediated Processing to Small Interfering RNA
RNAi by short hairpin RNA (shRNA) is a powerful tool not only for studying gene functions in various organisms, including mammals, but also for the treatment of severe disorders. However, shRNA-expressing vectors can induce type I interferon (IFN) expression by activation of innate immune responses,...
שמור ב:
| הוצא לאור ב: | Mol Ther Nucleic Acids |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Gene & Cell Therapy
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363498/ https://ncbi.nlm.nih.gov/pubmed/28325284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2016.12.007 |
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