Immunosuppressive Myeloid Cells’ Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy

Survival of glioma (GBM) patients treated with the current standard of care remains dismal. Immunotherapeutic approaches that harness the cytotoxic and memory potential of the host immune system have shown great benefit in other cancers. GBMs have developed multiple strategies, including the accumul...

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發表在:Mol Ther
Main Authors: Kamran, Neha, Kadiyala, Padma, Saxena, Meghna, Candolfi, Marianela, Li, Youping, Moreno-Ayala, Mariela A., Raja, Nicholas, Shah, Diana, Lowenstein, Pedro R., Castro, Maria G.
格式: Artigo
語言:Inglês
出版: American Society of Gene & Cell Therapy 2017
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363306/
https://ncbi.nlm.nih.gov/pubmed/28129117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.003
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