ME-10 TUMOR MICROENVIRONMENT INFILTRATING MYELOID DERIVED SUPPRESSOR CELLS INHIBIT ANTI-TUMOR T CELL RESPONSES

MDSCs represent a population of immature myeloid cells at various stages of differentiation that inhibit anti-tumor T cell-mediated responses. We demonstrate the accumulation of MDSCs in GL26 induced glioma and B16 melanoma bearing mice. Absolute numbers of Ly-6G(+) (Gr-1(high)) MDSCs showed a 200 f...

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Hauptverfasser: Kamran, Neha, Ayala, Mariela, Li, Youping, Assi, Hikmat, Candolfi, Marianela, Dzaman, Marta, Lowenstein, Pedro, Castro, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218311/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou261.9
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