Immunosuppressive Myeloid Cells’ Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy

Survival of glioma (GBM) patients treated with the current standard of care remains dismal. Immunotherapeutic approaches that harness the cytotoxic and memory potential of the host immune system have shown great benefit in other cancers. GBMs have developed multiple strategies, including the accumul...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Kamran, Neha, Kadiyala, Padma, Saxena, Meghna, Candolfi, Marianela, Li, Youping, Moreno-Ayala, Mariela A., Raja, Nicholas, Shah, Diana, Lowenstein, Pedro R., Castro, Maria G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363306/
https://ncbi.nlm.nih.gov/pubmed/28129117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.003
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