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Immunosuppressive Myeloid Cells’ Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy

Survival of glioma (GBM) patients treated with the current standard of care remains dismal. Immunotherapeutic approaches that harness the cytotoxic and memory potential of the host immune system have shown great benefit in other cancers. GBMs have developed multiple strategies, including the accumul...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Kamran, Neha, Kadiyala, Padma, Saxena, Meghna, Candolfi, Marianela, Li, Youping, Moreno-Ayala, Mariela A., Raja, Nicholas, Shah, Diana, Lowenstein, Pedro R., Castro, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363306/
https://ncbi.nlm.nih.gov/pubmed/28129117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.003
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